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New Zealand Biotech Industries News
2004/12/01

SHEEP PROVIDE FERTILITY CLUES

New contraceptives and treatments for infertility in women could be developed as a result of research being carried out by world experts in sheep fertility.

The research may also hold the key to future fertility treatments for other mammals, improved livestock production, and new opportunities for possum control.

AgResearch scientist Dr Jenny Juengel is studying sheep with naturally-occurring genetic variation affecting fertility, to find out exactly what causes differences in fertility and how it can be controlled.

Speaking at the annual molecular biology conference in Queenstown this week, Dr Juengel will expand on how valuable sheep are as a model for identifying new mechanisms to regulate fertility, and what this may mean for developing new therapeutics to regulate fertility in mammals.

Variations in fertility occur naturally across many species, and families of sheep carrying natural mutations associated with exceptional fertility were identified in the late 1970s. Animal breeding and genetics research, alongside molecular genetics and reproductive physiology lead to the discovery of specific genes, and the importance that proteins produced in the ovary play in regulating fertility.

This research is supported by Ovita Ltd, FRST and the Marsden Fund.

AgResearch Media Release, 1 December 2004

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